Interactive Assessment for Sickle Cell: Natural Selection in Humans: Interactive Video Builder: HHMI BioInteractive

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This film explores the evolutionary connection between an infectious disease, malaria, and a genetic condition, sickle cell disease.

Scientist Tony Allison first noticed a connection between malaria and the sickle cell trait while working in East Africa in the 1950s. His discovery is one of the best understood examples of natural selection in humans. The film also features two individuals who describe living with sickle cell disease and a hematologist, Natasha Archer, who describes the mechanism of how the sickle cell trait protects against malaria.

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Topics:: Human Evolution

Natural Selection

Genetic Disease

Patterns of Inheritance
Grade Levels:: College

High School — AP/IB

High School — General

This film explores the evolutionary connection between an infectious disease, malaria, and a genetic condition, sickle cell disease.

The film stops 11 times, and each time, a question will appear on the screen. You can check your answer and select a different answer. Watch the film until the end to download a PDF with your answers.